Clinical trials

For decades, the use of methods and tools is essential in the development of new drugs. Within the usual phases of clinical trials, the use of tools for the collection, integration, analysis and exchange of information, facilitates the process. In the after genome scientific arena and the emergence of thousands of private databases and public Internet access, it is necessary to develop new methodologies and tools. GIB is actively involved in ACGT (Advancing Clinico-Genomic Trials on Cancer), a project funded by the European Commission to develop new methods and tools for clinical trials in the after genome age. 25 partners from 13 countries participates in the project, in which the GIB has led research into new models of databases and the semantic interoperability of clinical databases, microarray and images. As a result of this work has been a semantic mediator and an ontology of cancer.

Clinical Trials_QueryTool

 

References:

  1. Maojo V, García-Remesal M, Billhardt H, Alonso-Calvo R, Pérez-Rey D, Martín-Sánchez F. Designing new methodologies for integrating biomedical information in clinical trials. Methods of Information in Medicine. 2006;45(2):180-5.
  2. Martín L, Anguita A, de la Calle G, García-Remesal M, Crespo J, Tsiknakis M, Maojo V. "Semantic Data Integration in the European ACGT project". Proceedings of the American Medical Informatics Association (AMIA - Annual Symposium) 2007. 11-14 Nov 2007, Chicago, IL (USA).
  3. Martín L, Bonsma E, Anguita A, Vrijnsen J, García-Remesal M, Crespo J, Tsiknakis M, Maojo V. "Data Access and Management in ACGT: Tools to solve syntactic and semantic heterogeneities between clinical and image databases". Proceedings of the First International Workshop on Conceptual Modelling for Life Sciences Applications (CMLSA 2007).